2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-18748
    BQR-695
    		Inhibitor 99.36%
    BQR-695 is a PI4KIIIβ inhibitor with IC50s of 80 and 3.5 nM for human PI4KIIIβ and Plasmodium variant of PI4KIIIβ, respectively.
    BQR-695
  • HY-111543
    AN11251
    		Inhibitor 99.45%
    AN11251 is a potent and oral active anti-Wolbachia agent with potential for treatment of onchocerciasis and lymphatic filariasis, with EC50 values of 1.5 nM in LDW1 cell lines and 15 nM in C6/36 cell lines.
    AN11251
  • HY-126323B
    TCMDC-135051 hydrochloride
    		Inhibitor 98.17%
    TCMDC-135051 hydrochloride is a highly selective and potent protein kinase PfCLK3 inhibitor with low off-target toxicity. TCMDC-135051 hydrochloride prevents trophozoite-to-schizont transition, disrupts transcription and reduces transmission to the mosquito vector. TCMDC-135051 hydrochloride has antiparasiticidal activity (EC50=320 nM).
    TCMDC-135051 hydrochloride
  • HY-111817
    ACT-451840
    		Inhibitor
    ACT-451840 is an orally active, potent and low-toxicity compound, showing activity against sensitive and resistant plasmodium falciparum strains. ACT-451840 targets all asexual blood stages of the parasite, has a rapid onset of action. ACT-451840 behaves in a way similar to artemisinin derivatives, with very rapid onset of action and elimination of parasite. ACT-451840 can be used for the research of malarial.
    ACT-451840
  • HY-78131CS
    Ibuprofen-d3 sodium
    		Inhibitor 99.21%
    Ibuprofen-d3 ((±)-Ibuprofen-d3) sodium is the deuterium labeled Ibuprofen sodium (HY-78131C). Ibuprofen sodium is an orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen sodium inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen sodium is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen sodium can be used in the research of pain, swelling, inflammation, infection, immunology, cancers.
    Ibuprofen-d<sub>3</sub> sodium
  • HY-16779
    Fosravuconazole
    		Inhibitor 99.86%
    Fosravuconazole (BMS-379224), a proagent of Ravuconazole, is an orally active broad spectrum antifungal agent. Fosravuconazole can be used for candidiasis, onychomycosis and parasitemia research.
    Fosravuconazole
  • HY-N1667
    2',4'-Dihydroxy-6'-Methoxyacetophenone
    		Inhibitor 99.58%
    2',4'-Dihydroxy-6'-Methoxyacetophenone is a phenolic acetophenone from Artemisia annua. Artemisia annua is an analog of Artemisinin that is effective in the research of malaria.
    2',4'-Dihydroxy-6'-Methoxyacetophenone
  • HY-W131282
    Antimalarial agent 39
    		Inhibitor
    Antimalarial agent 39 (compound 1) is an intermediate in the synthesis of antimalarial agents.
    Antimalarial agent 39
  • HY-B0318S
    Metronidazole-13C2,15N2
    		Inhibitor 99.30%
    Metronidazole-13C2,15N2 is the 13C-labeled and 15N-labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.
    Metronidazole-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N<sub>2</sub>
  • HY-162238
    OSM-S-106
    		Inhibitor 99.34%
    OSM-S-106 is a pro-inhibitor and that inhibition of PfAsnRS occurs via enzyme-mediated production of an Asn-OSM-S-106 adduct. OSM-S-106 inhibits protein translation and activates the amino acid starvation response. OSM-S-106 exhibits selective activity against Plasmodium blood and liver stages and low intrinsic clearance by human microsomes.
    OSM-S-106
  • HY-176707
    GS​​K2181306A
    		Inhibitor 99.17%
    GSK2181306A is a pan-FIKK inhibitor with an EC50 value of 0.16 μM for parasite growth inhibition. GSK2181306A can be used to study Plasmodium infection.
    GS​​K2181306A
  • HY-17592A
    Bithionol (sulfoxide)
    		Inhibitor 99.02%
    Bithionol sulfoxide is an anti-infection agent for parasites. Bithionol sulfoxide has mutagenic activity. Bithionol sulfoxide can be used in the research of parasite infection, such as paragonimiasis, flukes andcestodes infection.
    Bithionol (sulfoxide)
  • HY-125159
    Derquantel
    		Inhibitor 98.4%
    Derquantel, a spirocyclic anthelmintic, is a competitive, orally active nicotinic acetylcholine receptor (nAChR) antagonist. Derquantel inhibits ACh-induced depolarization with an IC50 of 0.22 μM. By selectively antagonizing nAChRs on the somatic muscles of nematodes, Derquantel causes flaccid paralysis of muscles, thereby dislodging parasites from the host's gastrointestinal tract. Derquantel is applicable to research related to Haemonchus contortus infection and Ascaris suum infection.
    Derquantel
  • HY-N7516
    4'-Hydroxy-2,4-dimethoxychalcone
    		Inhibitor 99.76%
    4'-Hydroxy-2,4-dimethoxychalcone is a natural chalcone derivatives in the red herbal resin of Dracaena cochinchinensis. 4'-Hydroxy-2,4-dimethoxychalcone displays a wide range of biological activities including antimalarial, antiprotozoal, antibacterial, antifungal activity.
    4'-Hydroxy-2,4-dimethoxychalcone
  • HY-B1437
    Acetarsol
    		Inhibitor 98.60%
    Acetarsol (Stovarsol) is a potent and orally active anti-infective agent. Acetarsol shows anti-parasite activity. Acetarsol has the potential for the research of proctitis.
    Acetarsol
  • HY-B0836R
    λ-Cyhalothrin (Standard)
    		Inhibitor
    λ-Cyhalothrin (Standard) is the analytical standard of λ-Cyhalothrin. This product is intended for research and analytical applications. λ-Cyhalothrin is a high efficiency, broad-spectrum type II synthetic pyrethroid insecticide containing α-cyano group. λ-Cyhalothrin is used to control a wide range of pests in a variety of applications. λ-Cyhalothrin is a neurotoxin that targets sodium channels in the membranes of neurons in the central nervous system.
    λ-Cyhalothrin (Standard)
  • HY-18715
    Ornidazole (Levo-)
    		Inhibitor 98.86%
    Levo-ornidazole ((S)-Ornidazole) is the L-isomer of Ornidazole. Ornidazole (Levo-) increases GAD 65/67 expression and decreases brain Glu/GABA ratio. Ornidazole (Levo-) has a mild sedative effect. Levo-ornidazole can be used in the research of anti-anaerobic and anti-parasitic agents.
    Ornidazole (Levo-)
  • HY-N2795
    9-Hydroxycalabaxanthone
    		Inhibitor 99.14%
    9-Hydroxycalabaxanthone (Xanthone I) is a known xanthone isolated from Garcinia mangostana Linn. 9-Hydroxycalabaxanthone has quorum-sensing inhibitory, anti-microbial, and anti-malarial activities (IC50=1.2-1.5 μM).
    9-Hydroxycalabaxanthone
  • HY-124481
    Oleocanthal
    		Inhibitor ≥99.0%
    Oleocanthal is an orally active phenolic seciridoid compound. Oleocanthal can be extracted from olive oil. Oleocanthal inhibits COX-1 and COX-2, reduces ROS and NO, and upregulates Nrf-2 and HO-1. Oleocanthal reduces Aβ deposition. Oleocanthal exhibits anti-Leishmania activity against promastigotes and amastigotes of L. major, with IC50 values of 18.7 and 87 μg/mL, respectively. Oleocanthal exhibits anticancer activity against colon, breast, liver, and melanoma cancers. Oleocanthal also exhibits anti-inflammatory and neuroprotective properties. Oleocanthal can be used in Alzheimer's disease research.
    Oleocanthal
  • HY-D0143B
    Quinine hemisulfate hydrate
    		Inhibitor 99.42%
    Quinine hemisulfate hydrate, an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine hemisulfate hydrate is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV, with an IC50 of 169 μM.
    Quinine hemisulfate hydrate
Parasite Isoform Comparison

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